After three rounds of competition - abstract acceptance, poster presentation, podium presentation - Three exceptional scientists became winners.
Reza B. Jalili - Winner
Development of an in situ-forming regenerative composite scaffold for treatment of diabetic wounds
Wound healing is a complex and dynamic process that involves not only cell-cell interaction, but also cell-matrix signaling. In chronic wounds, such as diabetic ulcers, persistent inflammatory condition and a lack of matrix deposition hinder normal heali...
Topical application of the novel biotherapeutic calreticulin heals diabetic wounds by a tissue regenerative process
The topical application of the ER chaperone protein calreticulin (CRT) enhances the rate and quality of wound healing in porcine and diabetic mouse models by enhancing cellular recruitment (keratinocytes, fibroblasts, and macrophages) and inducing abundant...
Small Molecule Antagonists of RAGE/DIAPH1 Interaction: Novel Therapeutic Opportunities in Impaired Wound Healing in Type 2 Diabetic Mice
Previous work in our laboratory has shown that administration of the soluble extracellular domains of the receptor for Advanced Glycation Endproducts, RAGE, thereby blocking the access of ligands to cell surface RAGE, restored effective wound healing in di...