master class cme on-demand learning

PRESENTATION SUMMARY

Dr. Bell's presentation will cover the following key points:

• Customized wound healing is possible if the body is provided components it needs for tissue repair.  
• Although every wound is unique, they all share common characteristics (edema, biofilm colonization, and decreased perfusion) which must be addressed for healing to occur.  
• Omega fatty acids and other naturally occurring substances provide antimicrobial properties that are non-cytotoxic and are not likely to demonstrate antimicrobial resistance.
  
  Dr. Bell will start by giving a brief review of how bacterial biofilms develop increased tolerance to immune cells antibiotics and many antiseptics, which leads to biofilms stimulating chronic inflammation with highly elevated levels of proteases and ROS that degrade proteins that are essential for healing.  He will then shift to review the “step down then step up” principle of biofilm based wound care that emphasizes early and effective debridement of wound biofilms and describe the new technique that selectively locates biofilms in chronic wound beds, describe new debridement treatments, and emphasize the importance of following debridement with several topical therapies that prevent reformation of biofilms and kill any residual biofilm bacteria. Dr. Bell will conclude by describing how to move to the “step up” phase of wound treatment by utilizing new treatments like topical oxygen therapy, advanced cell and tissue products and topical growth factors.

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Dr. Oropallo's talk will explore new methods, particularly imaging methods, for diagnosis of biofilm infections. Methods of combating biofilms will also be discussed.

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This talk explores the application of artificial intelligence (AI) for burn scar scoring

and wound classification, emphasizing that these AI methods can also be applied to

other types of scars and wounds. It covers how advanced machine learning

algorithms and computer vision techniques can be used to accurately assess the

severity and progression of burn scars and wounds. The discussion includes the

development and implementation of AI models trained on clinical datasets,

highlighting their potential to enhance diagnostic accuracy, streamline clinical

workflows, and improve patient outcomes. Additionally, real-world case studies and

recent advancements in AI technology are showcased to illustrate the practical

benefits and challenges associated with integrating AI into burn wound care and scar

management practices.

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Surgical site infection is the most prevalent and expensive complication associated with modern surgery. The existing approach for infection prevention relies on presurgical skin decolonization via aseptic skin washes. These washes, however, rely on harsh chemicals, such as chlorhexidine and iodine, that can be highly irritating and damaging to patient skin. Despite the implementation of these aseptic solutions, certain patient populations continue to remain at higher risk of infection, such as pediatrics, obese patients, and diabetics. Furthermore, novel approaches are necessary to elevate the quality of care for physiologically atypical patients. Here, we present an innovative strategy to surgical site infection prevention that leverages a novel molecule with dual anti-inflammatory and antimicrobial benefits, which is termed panthenol citrate. Panthenol citrate is a novel compound based on naturally occurring precursors panthenol and citric acid, which are common components within skin cleansers, lotions, and creams. The anti-inflammatory properties have been demonstrated as highly beneficial in multiple animal models for wound healing and elevating skin health. In this presentation, we discuss why anti-inflammatory properties are beneficial for infection prevention as well as wound healing, especially for patients that remain the most vulnerable to infection.

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Dr. Garcia's presentation is a review of current devices and technologies for lower limb revascularization for both above and below knee therapies

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